Impact of interleukin-10, soluble CD25 and interferon-γ on the prognosis and early diagnosis of bacteremic systemic inflammatory response syndrome: a prospective observational study

@inproceedings{Matera2013ImpactOI,
  title={Impact of interleukin-10, soluble CD25 and interferon-γ on the prognosis and early diagnosis of bacteremic systemic inflammatory response syndrome: a prospective observational study},
  author={Giovanni Matera and Rossana Puccio and Aida Giancotti and Angela Quirino and Maria Concetta Pulicari and Emilia Zicca and Santo Caroleo and Attilio Renzulli and Maria Carla Liberto and Alfredo Foc{\`a}},
  booktitle={Critical care},
  year={2013}
}
INTRODUCTION The pathophysiology of sepsis consists of two phases. A first phase characterized by a substantial increase of pro-inflammatory mediators including cytokines and systemic inflammatory markers, and a second phase (immunoparalysis, immunodysregulation) associated with the rise of anti-inflammatory mediators. In this study we prospectively analyzed 52 consecutive patients with diagnosis of systemic inflammatory response syndrome (SIRS) at hospital admission to evaluate prognostic and… CONTINUE READING

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