Impact of inappropriate antibiotic therapy on mortality in patients with ventilator-associated pneumonia and blood stream infection: a meta-analysis.

@article{Kuti2008ImpactOI,
  title={Impact of inappropriate antibiotic therapy on mortality in patients with ventilator-associated pneumonia and blood stream infection: a meta-analysis.},
  author={Effie L Kuti and Aarti A Patel and Craig I Coleman},
  journal={Journal of critical care},
  year={2008},
  volume={23 1},
  pages={91-100}
}
OBJECTIVES Studies have found that initial treatment of ventilator-associated pneumonia (VAP) and blood stream infections (BSI) with inappropriate antimicrobial therapy is associated with higher rates of mortality, but additional studies have failed to confirm this. METHODS Databases were searched to identify studies that met the following criteria: observational trials, patients with VAP or BSI receiving appropriate and inappropriate antimicrobial therapy, and mortality data. We conducted… CONTINUE READING

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