Impact of human immunodeficiency virus infection in pregnant women on variant-specific immunity to malaria.

@article{Dembo2008ImpactOH,
  title={Impact of human immunodeficiency virus infection in pregnant women on variant-specific immunity to malaria.},
  author={Edson G Dembo and Victor Mwapasa and Jacqui Montgomery and Alister G Craig and Kimberly A. Porter and Steven Richard Meshnick and Malcolm Edward Molyneux and Stephen J Rogerson},
  journal={Clinical and vaccine immunology : CVI},
  year={2008},
  volume={15 4},
  pages={617-21}
}
Human immunodeficiency virus (HIV) increases susceptibility to Plasmodium falciparum infection, and this has most clearly been demonstrated in pregnant women. Variant surface antigens on the surfaces of erythrocytes infected with P. falciparum are major targets of protective immunity. We studied the impact of HIV infection on pregnant women's humoral immunity to variant surface antigens expressed by placental and pediatric isolates of P. falciparum. By flow cytometry, sera from HIV-infected… CONTINUE READING

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