Impact of genetic vulnerability and hypoxia on overall intelligence by age 7 in offspring at high risk for schizophrenia compared with affective psychoses.

@article{Goldstein2000ImpactOG,
  title={Impact of genetic vulnerability and hypoxia on overall intelligence by age 7 in offspring at high risk for schizophrenia compared with affective psychoses.},
  author={Jill M. Goldstein and Larry J. Seidman and Stephen L. Buka and Nicholas J. Horton and Jo{\~a}o L. Donatelli and Ronald O. Rieder and Ming T. Tsuang},
  journal={Schizophrenia bulletin},
  year={2000},
  volume={26 2},
  pages={323-34}
}
Risk factors for schizophrenia, such as genetic vulnerability and obstetric complications, have been associated with cognitive deficits in schizophrenia. We tested the association of these risk factors with general intellectual ability in offspring at high risk for psychoses and normal control subjects. Offspring of 182 parents with DSM-IV schizophrenia or affective psychoses were recruited and diagnosed from the Boston and Providence cohorts of the National Collaborative Perinatal Project… CONTINUE READING
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