Impact of genetic similarity on imputation accuracy

  title={Impact of genetic similarity on imputation accuracy},
  author={Nab Raj Roshyara and Markus Scholz},
  booktitle={BMC Genetics},
Genotype imputation is a common technique in genetic research. Genetic similarity between target population and reference dataset is crucial for high-quality results. Although several reference panels are available, it is often not clear which is the most optimal for a particular target dataset to be imputed. Maximizing genetic similarity between study sample and intended reference panels may be the straight forward method for selecting the genetically best-matched reference. However, the… CONTINUE READING
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