Impact of genetic polymorphisms in thrombin activatable fibrinolysis inhibitor (TAFI) on venous thrombosis disease: A meta-analysis.

@article{Qian2015ImpactOG,
  title={Impact of genetic polymorphisms in thrombin activatable fibrinolysis inhibitor (TAFI) on venous thrombosis disease: A meta-analysis.},
  author={Kai Qian and Jie Xu and Heng Wan and Fangyong Fu and Jingbo Lu and Zhiqi Lin and Zhengjun Liu and Hao Liu},
  journal={Gene},
  year={2015},
  volume={569 2},
  pages={
          173-81
        }
}
  • Kai Qian, Jie Xu, +5 authors Hao Liu
  • Published in Gene 2015
  • Biology, Medicine
  • BACKGROUND Reported studies have showed that Thrombin Activatable Fibrinolysis Inhibitor (TAFI) may be associated with an increased risk of venous thromboembolism. But the relation of VT with TAFI gene SNPs could not be clearly demonstrated. Thus, we conducted a meta-analysis to analyze the associations between three TAFI variants -438G/A, 505G/A and 1040C/T and the risk of venous thrombosis. METHODS We carried out a systematic search to obtain all the eligible studies published before 30th… CONTINUE READING

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