Impact of genetic features on treatment decisions in AML.

  title={Impact of genetic features on treatment decisions in AML.},
  author={Hartmut D{\"o}hner and Verena Ingeborg Gaidzik},
  journal={Hematology. American Society of Hematology. Education Program},
In recent years, research in molecular genetics has been instrumental in deciphering the molecular pathogenesis of acute myeloid leukemia (AML). With the advent of the novel genomics technologies such as next-generation sequencing, it is expected that virtually all genetic lesions in AML will soon be identified. Gene mutations or deregulated expression of genes or sets of genes now allow us to explore the enormous diversity among cytogenetically defined subsets of AML, in particular the large… CONTINUE READING

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