Impact of first-line vs second-line antibiotics for the treatment of acute uncomplicated sinusitis.

@article{Piccirillo2001ImpactOF,
  title={Impact of first-line vs second-line antibiotics for the treatment of acute uncomplicated sinusitis.},
  author={Jay F. Piccirillo and D E Mager and Mark E. Frisse and R H Brophy and A Goggin},
  journal={JAMA},
  year={2001},
  volume={286 15},
  pages={1849-56}
}
CONTEXT Studies suggest little benefit in relief of acute sinusitis symptoms from the use of newer and more expensive (second-line) antibiotics instead of older and less expensive (first-line) antibiotics. However, researchers have failed to include development of complications and cost of care in their analyses. OBJECTIVE To compare the effectiveness and cost of first-line with second-line antibiotics for the treatment of acute uncomplicated sinusitis in adults. DESIGN, SETTING, AND… CONTINUE READING

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