Impact of estradiol on gamma-aminobutyric acid- and glutamate-mediated calcium responses of fetal baboon (Papio anubis) hippocampal and cortical neurons.

@article{Nuez2008ImpactOE,
  title={Impact of estradiol on gamma-aminobutyric acid- and glutamate-mediated calcium responses of fetal baboon (Papio anubis) hippocampal and cortical neurons.},
  author={Joseph L. Nu{\~n}ez and Graham W. Aberdeen and Eugene D. Albrecht and Margaret M McCarthy},
  journal={Endocrinology},
  year={2008},
  volume={149 12},
  pages={6433-43}
}
High levels of maternal estrogens are likely to gain access to the fetal brain, yet little is known regarding the role of the steroid hormone 17beta-estradiol in neuronal differentiation and maturation of primate neurons. Previous research documented the presence of estrogen receptors during development in the hippocampus and cortex of the primate brain, but the functional significance of steroid exposure has not been widely investigated. Using both an in vitro preparation of primary… CONTINUE READING