Impact of ertapenem use on Pseudomonas aeruginosa and Acinetobacter baumannii imipenem susceptibilit

@article{Sousa2013ImpactOE,
  title={Impact of ertapenem use on Pseudomonas aeruginosa and Acinetobacter baumannii imipenem susceptibilit},
  author={Dolores Sousa and Laura Castelo-Corral and Jos{\'e}-Mar{\'i}a Guti{\'e}rrez-Urb{\'o}n and Francisca Molina and Beatriz L{\'o}pez-Calvi{\~n}o and Germ{\'a}n Bou and Pedro Llinares},
  journal={The Journal of antimicrobial chemotherapy},
  year={2013},
  volume={68 8},
  pages={1917-25}
}
BACKGROUND Conflicting evidence has been reported on the impact of ertapenem use on the susceptibility of Pseudomonas spp. to group 2 carbapenems. No extensive data for Acinetobacter baumannii are currently available. METHODS A retrospective time-series segmented regression analysis was conducted in a tertiary centre from January 2001 to December 2011. Ertapenem was introduced in January 2005. Antimicrobial drug use was defined as the number of defined daily doses/100 patient-days (DDDs/100… CONTINUE READING

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