Impact of early administration of sertraline on depressive symptoms in the first year after traumatic brain injury.

@article{Novack2009ImpactOE,
  title={Impact of early administration of sertraline on depressive symptoms in the first year after traumatic brain injury.},
  author={Thomas A Novack and James H Ba{\~n}os and Robert Brunner and Sharon G. Renfroe and Jay M Meythaler},
  journal={Journal of neurotrauma},
  year={2009},
  volume={26 11},
  pages={1921-8}
}
The potential for sertraline administered in the first 3 months after moderate to severe traumatic brain injury (TBI) to decrease the incidence of depression in the first year after injury was assessed in a double-blinded randomized control trial. Subjects were enrolled an average of 21 days after injury (none >8 weeks) followed by oral administration of placebo (50 subjects) or sertraline 50 mg (49 subjects) for 3 months. Subjects were not depressed at the time of study initiation. Outcome was… CONTINUE READING
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