Impact of craniospinal dose, boost volume, and neurologic complications on intellectual outcome in patients with medulloblastoma.

@article{MoxonEmre2014ImpactOC,
  title={Impact of craniospinal dose, boost volume, and neurologic complications on intellectual outcome in patients with medulloblastoma.},
  author={Iska Moxon-Emre and Eric Bouffet and Michael D. Taylor and Normand Laperriere and Nadia Scantlebury and Nicole Law and Brenda J. Spiegler and David Malkin and Laura A Janzen and Donald J Mabbott},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2014},
  volume={32 17},
  pages={
          1760-8
        }
}
PURPOSE To examine the impact of radiation (ie, craniospinal irradiation [CSR] dose and boost volume) and complications (ie, hydrocephalus and other neurologic complications, including mutism) on patterns of change in intellectual functioning in medulloblastoma survivors. PATIENTS AND METHODS We conducted a retrospective review of 113 patients treated for medulloblastoma between 1983 and 2011 who were seen for neuropsychological assessment, including longitudinal follow-up of intellectual… CONTINUE READING
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