Impact of counterbalance between macrophage migration inhibitory factor and its inhibitor Gremlin-1 in patients with coronary artery disease.

@article{Mueller2014ImpactOC,
  title={Impact of counterbalance between macrophage migration inhibitory factor and its inhibitor Gremlin-1 in patients with coronary artery disease.},
  author={Iris Mueller and Karin Anne Lydia Mueller and Athanasios Karathanos and Heiko Schoenleber and Dominik Rath and Sebastian Vogel and Madhumita Chatterjee and Martina Schmid and Maximilian Haas and Peter Seizer and Harald F Langer and Elke Schaeffeler and Matthias Schwab and Meinrad Paul Gawaz and T Robert Geisler},
  journal={Atherosclerosis},
  year={2014},
  volume={237 2},
  pages={426-32}
}
OBJECTIVE Monocyte infiltration is a critical step in the pathophysiology of plaque instability in coronary artery disease (CAD). Macrophage migration inhibitory factor (MIF) is involved in atherosclerotic plaque progression and instability leading to intracoronary thrombosis. Gremlin-1 (Grem1) has been recently identified as endogenous inhibitor of MIF. To… CONTINUE READING