Impact of computational approaches in the fight against COVID-19: an AI guided review of 17 000 studies
@article{Napolitano2022ImpactOC, title={Impact of computational approaches in the fight against COVID-19: an AI guided review of 17 000 studies}, author={Francesco Napolitano and Xiaopeng Xu and Xin Gao}, journal={Briefings in Bioinformatics}, year={2022} }
Abstract SARS-CoV-2 caused the first severe pandemic of the digital era. Computational approaches have been ubiquitously used in an attempt to timely and effectively cope with the resulting global health crisis. In order to extensively assess such contribution, we collected, categorized and prioritized over 17 000 COVID-19-related research articles including both peer-reviewed and preprint publications that make a relevant use of computational approaches. Using machine learning methods, we…
2 Citations
Towards a Unified Pandemic Management Architecture: Survey, Challenges and Future Directions
- Computer ScienceArXiv
- 2022
A unified pandemic management architecture is envisioned that leverages the IoT and edge computing to automate recommendations on vaccine distribution, dynamic lockdown, mobility scheduling and pandemic prediction, and elucidate the flow of data among the layers of the architecture.
2′- and 3′-Ribose Modifications of Nucleotide Analogues Establish the Structural Basis to Inhibit the Viral Replication of SARS-CoV-2
- Biology, ChemistryThe journal of physical chemistry letters
- 2022
The results suggest that 2′-modification couples with the protein environment to affect the structural stability, while 3′-hydrogen substitution inherently exerts “immediate termination” without compromising theStructural stability in the active site.
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