Impact of clinical trials on clinical practice: example of thrombolysis for acute myocardial infarction.

@article{Ketley1993ImpactOC,
  title={Impact of clinical trials on clinical practice: example of thrombolysis for acute myocardial infarction.},
  author={Diane Ketley and Kent L Woods},
  journal={Lancet},
  year={1993},
  volume={342 8876},
  pages={891-4}
}
Little is known about incorporation of new knowledge from randomised clinical trials into clinical practice. Thrombolytic therapy was shown to reduce the mortality of acute myocardial infarction in several large trials published during 1986-88. To examine the effect of these data on clinical practice, we analysed the supply of thrombolytic drugs in a representative English region (population 4.7 million) in 1987-92. During the study period there were over 10,000 hospital admissions per year in… CONTINUE READING