Impact of cholesterol on voids in phospholipid membranes.

  title={Impact of cholesterol on voids in phospholipid membranes.},
  author={E. Falck and M. Patra and M. Karttunen and M. T. Hyv{\"o}nen and I. Vattulainen},
  journal={The Journal of chemical physics},
  volume={121 24},
  • E. Falck, M. Patra, +2 authors I. Vattulainen
  • Published 2004
  • Medicine, Physics, Chemistry
  • The Journal of chemical physics
  • Free volume pockets or voids are important to many biological processes in cell membranes. Free volume fluctuations are a prerequisite for diffusion of lipids and other macromolecules in lipid bilayers. Permeation of small solutes across a membrane, as well as diffusion of solutes in the membrane interior are further examples of phenomena where voids and their properties play a central role. Cholesterol has been suggested to change the structure and function of membranes by altering their free… CONTINUE READING
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