Impact of chemotherapeutics and advanced testicular cancer or Hodgkin lymphoma on sperm deoxyribonucleic acid integrity.

@article{OFlaherty2010ImpactOC,
  title={Impact of chemotherapeutics and advanced testicular cancer or Hodgkin lymphoma on sperm deoxyribonucleic acid integrity.},
  author={Cristian O'Flaherty and Barbara F. Hales and Peter Chan and Bernard Robaire},
  journal={Fertility and sterility},
  year={2010},
  volume={94 4},
  pages={
          1374-9
        }
}
OBJECTIVE To determine the impact of combination chemotherapy on the quality of newly generated spermatozoa from patients with advanced testicular cancer and patients with Hodgkin lymphoma (HL). DESIGN Prospective longitudinal study. SETTING Academic facility. PATIENT(S) Patients with newly diagnosed metastatic testicular cancer and with HL that required chemotherapy were compared with age-matched healthy community volunteers. INTERVENTION(S) None. MAIN OUTCOME MEASURE(S) Semen… CONTINUE READING
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