Impact of carbamylation and glycation of collagen type I on migration of HT1080 human fibrosarcoma cells.

Abstract

Collagen type I is an abundant component of the extracellular matrix and due to its longevity, constitutes a prominent target of non-enzymatic post-translational in vivo modifications such as carbamylation and glycation. These protein modifications involved in aging, renal diseases and diabetes, are linked to elevated cancer risk. In this in vitro study, we… (More)
DOI: 10.3892/ijo.2012.1393

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