Impact of blood rheology on wall shear stress in a model of the middle cerebral artery

  title={Impact of blood rheology on wall shear stress in a model of the middle cerebral artery},
  author={M. Bernabeu and R. Nash and D. Groen and Hywel B. Carver and J. Hetherington and T. Kr{\"u}ger and P. Coveney},
  journal={Interface Focus},
  • M. Bernabeu, R. Nash, +4 authors P. Coveney
  • Published 2013
  • Medicine, Computer Science, Physics
  • Interface Focus
  • Perturbations to the homeostatic distribution of mechanical forces exerted by blood on the endothelial layer have been correlated with vascular pathologies, including intracranial aneurysms and atherosclerosis. Recent computational work suggests that, in order to correctly characterize such forces, the shear-thinning properties of blood must be taken into account. To the best of our knowledge, these findings have never been compared against experimentally observed pathological thresholds. In… CONTINUE READING
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