Impact of blood rheology on wall shear stress in a model of the middle cerebral artery

M. Bernabeu; R. Nash; D. Groen; Hywel B. Carver; J. Hetherington; T. Krüger; P. Coveney

DOI:10.1098/rsfs.2012.0094

Corpus ID: 12474510

Impact of blood rheology on wall shear stress in a model of the middle cerebral artery

@article{Bernabeu2013ImpactOB,
  title={Impact of blood rheology on wall shear stress in a model of the middle cerebral artery},
  author={M. Bernabeu and R. Nash and D. Groen and Hywel B. Carver and J. Hetherington and T. Kr{\"u}ger and P. Coveney},
  journal={Interface Focus},
  year={2013},
  volume={3}
}

M. Bernabeu, R. Nash, +4 authors P. Coveney

Published 2013

Medicine, Computer Science, Physics

Interface Focus

Perturbations to the homeostatic distribution of mechanical forces exerted by blood on the endothelial layer have been correlated with vascular pathologies, including intracranial aneurysms and atherosclerosis. Recent computational work suggests that, in order to correctly characterize such forces, the shear-thinning properties of blood must be taken into account. To the best of our knowledge, these findings have never been compared against experimentally observed pathological thresholds. In… CONTINUE READING

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