Impact of beta blockers on epithelial ovarian cancer survival.

  title={Impact of beta blockers on epithelial ovarian cancer survival.},
  author={Elena S Diaz and Beth Y. Karlan and Andrew John Li},
  journal={Gynecologic oncology},
  volume={127 2},
OBJECTIVE Stress may promote ovarian cancer progression through mechanisms including autonomic nervous system mediators such as norepinephrine and epinephrine. Beta blockers, used to treat hypertension, block production of these adrenergic hormones, and have been associated with prolonged survival in several malignancies. We sought to determine the association between beta blocker use and epithelial ovarian cancer (EOC) disease progression and survival. METHODS We performed an institutional… CONTINUE READING
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