Impact of bacteria and bacterial components on osteogenic and adipogenic differentiation of adipose-derived mesenchymal stem cells.

@article{Fiedler2013ImpactOB,
  title={Impact of bacteria and bacterial components on osteogenic and adipogenic differentiation of adipose-derived mesenchymal stem cells.},
  author={Tomas Fiedler and A. Salamon and S. Adam and Nicole Herzmann and J. Taubenheim and K. Peters},
  journal={Experimental cell research},
  year={2013},
  volume={319 18},
  pages={
          2883-92
        }
}
Adult mesenchymal stem cells (MSC) are present in several tissues, e.g. bone marrow, heart muscle, brain and subcutaneous adipose tissue. In invasive infections MSC get in contact with bacteria and bacterial components. Not much is known about how bacterial pathogens interact with MSC and how contact to bacteria influences MSC viability and differentiation potential. In this study we investigated the impact of three different wound infection relevant bacteria, Escherichia coli, Staphylococcus… Expand
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