Impact of atrial high-rate episodes on the risk of future stroke.

  title={Impact of atrial high-rate episodes on the risk of future stroke.},
  author={Miyo Nakano and Yusuke Kondo and Masahiro Nakano and Takatsugu Kajiyama and Tomohiko Hayashi and Ryo Ito and Haruhiro Takahira and Yoshio Kobayashi},
  journal={Journal of cardiology},
  volume={74 2},
BACKGROUND Atrial fibrillation (AF) is the most common type of arrhythmia. The definition of AF in patients with cardiac implantable electronic devices (CIEDs) is not clear, and the appropriate treatment guideline for patients with episodes of AF has not been established yet. Additionally, little is known about the incidence of AF and embolic stroke events in Japanese patients with CIEDs. The purposes of this study were to identify the incidence of embolic stroke events in Japanese patients… Expand
Predictive value of left atrial function for latent paroxysmal atrial fibrillation as the cause of embolic stroke of undetermined source.
LA strain was significantly associated with new development of AF and patients with impaired LA function at admission should be carefully monitored to find AF. Expand
Association Between Atrial High-Rate Episodes and Ischemic/Major Bleeding Events in Patients With a Cardiac Implantable Electronic Device - A 10-Year, Single-Center Historical Cohort Study.
Longer AHRE duration is associated with a high number of major bleeding and ischemic events, and monitoring these bleeding risks is mandatory when clinicians are considering anticoagulation therapy for patients who underwent a cardiac implantable electronic device (CIED) procedure. Expand
Duration of atrial high-rate episodes and CHA2DS2-VASc score to predict cardiovascular and cerebrovascular events in patients with dual chamber permanent pacemakers.
The combination of AHRE duration ≥30 seconds and CHA2DS2-VASc score ≥2 (males) or ≥3 (females) is a useful risk-stratification predictor for subsequent CCE. Expand
The role of antithrombotic therapy in heart failure.
Evidence regarding the thrombotic risk and the role of antiplatelet and anticoagulant agents in patients with heart failure is summarized and current evidence about their role in heart failure with sinus rhythm is inconclusive and further research is needed. Expand
Left ventricular stiffness assessed by diastolic Wall strain predicts asymptomatic atrial high-rate episodes in patients with pacemaker implantation.
LV stiffness assessed by DWS was associated with AHREs in patients with a dual-chamber pacemaker (PMI), and on multivariable analysis, only D WS was independently associated withAHREs. Expand
The optimal cutoff of atrial high‐rate episodes for neurological events in patients with dual chamber permanent pacemakers
  • Wei-Da Lu, Ju-Yi Chen
  • Medicine
  • Clinical cardiology
  • 2021
This study aimed to identify the optimal cutoff threshold for AHRE duration in patients with dual chamber permanent pacemakers (PPM) without prior atrial fibrillation. Expand
Corundum of stroke risk in atrial high rate episodes.


Clinical significance of atrial high-rate episodes for thromboembolic events in Japanese population
AHREs detected by pacemaker were associated with ischaemic stroke/SE in the Japanese population, however, this association was observed only in the high thromboembolic risk group. Expand
Stroke risk in patients with device-detected atrial high-rate episodes
The notion that AHRE and stroke coincide perseveres but should be abandoned since CIED data show a clear disconnect is abandoned, and intensifying CIED read-outs can be considered to find progression in AHRE duration sooner, enhancing timely stroke prevention. Expand
Atrial Fibrillation Burden and Short-Term Risk of Stroke: Case-Crossover Analysis of Continuously Recorded Heart Rhythm From Cardiac Electronic Implanted Devices
In this population of patients with continuous heart rhythm recording with cardiac implantable electronic devices, multiple hours of AF had a strong but transient effect raising stroke risk. Expand
Device-detected atrial fibrillation and risk for stroke: an analysis of >10 000 patients from the SOS AF project (Stroke preventiOn Strategies based on Atrial Fibrillation information from implanted devices)
Device-detected AF burden is associated with an increased risk of ischaemic stroke in a relatively unselected population of CIEDs patients, and this finding may add to the basis for timely and clinically appropriate decision-making on anticoagulation treatment. Expand
Detection of previously undiagnosed atrial fibrillation in patients with stroke risk factors and usefulness of continuous monitoring in primary stroke prevention.
Whether patients with CHADS(2) risk factors but without a history of AF might benefit from implantable monitors for the selection and administration of anticoagulation for primary stroke prevention merits additional investigation. Expand
Subclinical atrial fibrillation and the risk of stroke.
Subclinical atrial tachyarrhythmias, without clinical atrial fibrillation, occurred frequently in patients with pacemakers and were associated with a significantly increased risk of ischemic stroke or systemic embolism. Expand
Temporal Relationship Between Subclinical Atrial Fibrillation and Embolic Events
Although SCAF is associated with an increased risk of stroke and embolism, very few patients had SCAF in the month before their event, and only 1 of these 4 patients was experiencing SCAF at the time of the stroke. Expand
Management of atrial high-rate episodes detected by cardiac implanted electronic devices
A management algorithm is proposed that takes into account both the stroke risk and the AHRE burden, but highlights the current uncertainty and evidence gaps for this condition. Expand
Covert atrial fibrillation and atrial high-rate episodes as a potential cause of embolic strokes of undetermined source: Their detection and possible management strategy.
Covert atrial fibrillation and atrial high-rate episodes detected by cardiac implantable electronic devices are believed to contribute to the pathogenesis of cryptogenic ischemic stroke or ESUS. Expand
The Relationship Between Daily Atrial Tachyarrhythmia Burden From Implantable Device Diagnostics and Stroke Risk: The TRENDS Study
The data suggest that TE risk is a quantitative function of AT/AF burden, and patients with traditional AF with similar risk profiles receiving pacemakers or defibrillators that monitor atrial tachycardia burden appear to double TE risk. Expand