Impact of anesthetic regimen on the respiratory pattern, EEG microstructure and sleep in the rat model of cholinergic Parkinson's disease neuropathology.

@article{Lazic2015ImpactOA,
  title={Impact of anesthetic regimen on the respiratory pattern, EEG microstructure and sleep in the rat model of cholinergic Parkinson's disease neuropathology.},
  author={Katarina Lazic and Jelena Petrovi{\'c} and Jelena Ciric and A. Kalauzi and Jasna Saponjic},
  journal={Neuroscience},
  year={2015},
  volume={304},
  pages={1-13}
}
OBJECTIVES We hypothesized that the impact of distinct anesthetic regimens could be differently expressed during anesthesia and on post-anesthesia sleep in the neurodegenerative diseases. Therefore, we followed the impact of ketamine/diazepam and pentobarbital anesthesia in a rat model of the severe Parkinson's disease cholinergic neuropathology on the electroencephalographic (EEG) microstructure and respiratory pattern during anesthesia, and on the post-anesthesia sleep. METHODS We performed… CONTINUE READING