Impact of aging on hippocampal function: plasticity, network dynamics, and cognition

@article{Rosenzweig2003ImpactOA,
  title={Impact of aging on hippocampal function: plasticity, network dynamics, and cognition},
  author={Ephron S. Rosenzweig and Carol A. Barnes},
  journal={Progress in Neurobiology},
  year={2003},
  volume={69},
  pages={143-179}
}
Aging is associated with specific impairments of learning and memory, some of which are similar to those caused by hippocampal damage. Studies of the effects of aging on hippocampal anatomy, physiology, plasticity, and network dynamics may lead to a better understanding of age-related cognitive deficits. Anatomical and electrophysiological studies indicate that the hippocampus of the aged rat sustains a loss of synapses in the dentate gyrus, a loss of functional synapses in area CA1, a decrease… CONTINUE READING
Highly Influential
This paper has highly influenced 17 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 281 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 91 references

Similar Papers

Loading similar papers…