Impact of aging on hippocampal function: plasticity, network dynamics, and cognition

@article{Rosenzweig2003ImpactOA,
  title={Impact of aging on hippocampal function: plasticity, network dynamics, and cognition},
  author={E. Rosenzweig and C. Barnes},
  journal={Progress in Neurobiology},
  year={2003},
  volume={69},
  pages={143-179}
}
Aging is associated with specific impairments of learning and memory, some of which are similar to those caused by hippocampal damage. Studies of the effects of aging on hippocampal anatomy, physiology, plasticity, and network dynamics may lead to a better understanding of age-related cognitive deficits. Anatomical and electrophysiological studies indicate that the hippocampus of the aged rat sustains a loss of synapses in the dentate gyrus, a loss of functional synapses in area CA1, a decrease… Expand
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