Impact of age-related immune dysfunction on risk of infections

@article{Castle2000ImpactOA,
  title={Impact of age-related immune dysfunction on risk of infections},
  author={Steven Charles Castle},
  journal={Zeitschrift f{\"u}r Gerontologie und Geriatrie},
  year={2000},
  volume={33},
  pages={341-349}
}
  • Steven Charles Castle
  • Published in
    Zeitschrift für Gerontologie…
    2000
  • Medicine
  • Summary The elderly have clearly been found to have both increased risk and severity of infections. Immunosenescence, the state of dysregulated immune function with aging, is felt to be a significant contributor to this increased risk. Extensive studies on inbred laboratory animals and in very healthy elderly humans have identified changes in immunity and have identified primarily phenotypic and functional changes in the T cell component of adaptive immunity. However, no compelling scientific… CONTINUE READING

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