Impact of age on outcomes after initial therapy with chemotherapy and different chemoimmunotherapy regimens in patients with chronic lymphocytic leukemia: results of sequential cancer and leukemia group B studies.


PURPOSE Chronic lymphocytic leukemia (CLL) is a disease of the elderly, yet few clinical trials include a significant number of older patients, and outcomes after specific therapies can be different depending on age. PATIENTS AND METHODS We examined patients enrolled onto successive first-line CALGB CLL trials to determine whether efficacy of regimens… (More)
DOI: 10.1200/JCO.2011.41.5646


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