Impact of a conservative red blood cell transfusion strategy in children undergoing hematopoietic stem cell transplantation.

@article{Lightdale2012ImpactOA,
  title={Impact of a conservative red blood cell transfusion strategy in children undergoing hematopoietic stem cell transplantation.},
  author={Jenifer R. Lightdale and Adrienne G Randolph and Chau M Tran and Hongyu Jeanne Jiang and Andrea Colon and Kathleen E Houlahan and Amy L Billet and Steven R. Sloan and Leslie E. Lehmann},
  journal={Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation},
  year={2012},
  volume={18 5},
  pages={813-7}
}
A 2008 randomized trial of critically ill, but stable, children reported the safety of transfusing red blood cells at a hemoglobin threshold of 7 g/dL. In 2009, we adopted the same transfusion criteria in our hematopoietic stem cell transplantation patients. Regression modeling was used to compare data obtained during primary admission for hematopoietic stem cell transplantation in calendar years before and after our practice change. Sixty-six patients admitted in the preintervention year were… CONTINUE READING