Impact of a CART promoter genetic variation on plasma lipid profile in a general population.

@article{Vasseur2007ImpactOA,
  title={Impact of a CART promoter genetic variation on plasma lipid profile in a general population.},
  author={Francis Vasseur and Audrey Gu{\'e}rardel and Mouna Barat-Houari and Dominique Cottel and Philippe Amouyel and Philippe Froguel and Nicole Helbecque},
  journal={Molecular genetics and metabolism},
  year={2007},
  volume={90 2},
  pages={199-204}
}
The cocaine and amphetamine regulated transcript (CART), an anorexigenic peptide responding to leptin, is expressed in various areas of the hypothalamus. The role of CART in humans and its potential contribution to abnormalities in feeding control are mostly unknown. Since CART plays an important role in the hypothalamic regulation of energy balance by reducing food intake and increasing lipid substrate utilization, it might affect cholesterol metabolism as Neuropeptide Y or pro… CONTINUE READING