Impact of Vitamin D in the Treatment of Tuberculosis

@article{Lng2011ImpactOV,
  title={Impact of Vitamin D in the Treatment of Tuberculosis},
  author={Khanh vinh quốc Lương and Lan Thị H{\`o}ang Nguyễn},
  journal={The American Journal of the Medical Sciences},
  year={2011},
  volume={341},
  pages={493-498}
}
  • K. Lương, L. Nguyễn
  • Published 1 June 2011
  • Medicine, Biology
  • The American Journal of the Medical Sciences
Tuberculosis (TB) is a major global health problem and often coincides with nutritional deficiency. In fact, vitamin D deficiency has been reported among TB patients, and vitamin D receptor polymorphisms are associated with susceptibility to Mycobacterium tuberculosis. High doses of vitamin D were widely used to treat TB patients in the preantibiotic era. This approach was successful: vitamin D can suppress intracellular growth of M tuberculosis in vitro. Vitamin D also induced the expression… 
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31 Citations
Highly Influential Citations
1
Background Citations
12
Methods Citations
1

31 Citations

Citation Type

Citation Type

Impact of Vitamin D in Prophylaxis and Treatment in Tuberculosis Patients
TLDR
It would be advisable to assess vitamin D level both in patients with active TB and high-risk groups and administer it, at least to reach sufficiency levels, considering the low incidence of side effects even at high dosages and its low cost.
Vitamin D and tuberculosis
TLDR
The role that vitamin D plays in tuberculosis has also been demonstrated by its effects on Bacillus Calmette Guerin, vascular endothelial growth factor, matrix metalloproteinases, prostaglandins, reactive oxygen species, and reactive nitrogen intermediates, in addition to its synergistic effects with some anti-tuberculosis medications.
Potential Role of Vitamins A, B, C, D and E in TB Treatment and Prevention: A Narrative Review
TLDR
Vitamin supplementation as a prophylactic measure in those who are at high risk of Mycobacterium tuberculosis (MTB) infection and active TB is suggested and the use of vitamins in TB patients is encouraged.
Estimation of some Immunological Factors in Pulmonary Tuberculosis Patients
TLDR
A good correlation between the levels of IL-10 , IL-12, IFN-γ and Vitamin D3 with the cellular immunity against pulmonary tuberculosis is provided.
Vitamin D in Oncology
  • J. Arends
  • Medicine, Biology
    Complementary Medicine Research
  • 2011
TLDR
While supplements of vitamin D improve musculoskeletal symptoms, proof is still lacking that these doses convey a protection from cancer, Interventional studies that administer vitamin D versus placebo in patients with cancer should be a high priority.
The effects of first-line anti-tuberculosis drugs on the actions of vitamin D in human macrophages
Vitamin D status in pediatric osteoarticular tuberculosis.
Influence of vitamin D deficiency on T cell subsets and related indices during spinal tuberculosis
TLDR
The expression of T lymphocyte subsets in patients with vitamin D deficiency was significantly reduced, and the immune function decreased, which was not conducive to the recovery of tuberculosis lesions.
Avaliação das concentrações de vitamina D associadas a polimorfismos em genes ligados a resposta imune durante a tuberculose pulmonar ativa
TLDR
Evidence is provided of the association between VDR SNPs and Gc-globulin and serum of 25(OH)D how possible protective factors against TB and also susceptibility in Brazilian population.
Prevalence of vitamin D deficiency in adults in the coastal regions of Odisha, India
TLDR
Regular serum vitamin D status must be assessed to review the nutritional status in apparently healthy population and in musculoskeletal diseases, suggesting that Vitamin D supplementation may be introduced along with regular monitoring may be included in the health care management.
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References

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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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