Impact of Vitamin D in the Treatment of Tuberculosis

@article{Lng2011ImpactOV,
  title={Impact of Vitamin D in the Treatment of Tuberculosis},
  author={Khanh vinh quốc Lương and Lan Thị H{\`o}ang Nguyễn},
  journal={The American Journal of the Medical Sciences},
  year={2011},
  volume={341},
  pages={493-498}
}
Tuberculosis (TB) is a major global health problem and often coincides with nutritional deficiency. In fact, vitamin D deficiency has been reported among TB patients, and vitamin D receptor polymorphisms are associated with susceptibility to Mycobacterium tuberculosis. High doses of vitamin D were widely used to treat TB patients in the preantibiotic era. This approach was successful: vitamin D can suppress intracellular growth of M tuberculosis in vitro. Vitamin D also induced the expression… 
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Vitamin D and tuberculosis
TLDR
The role that vitamin D plays in tuberculosis has also been demonstrated by its effects on Bacillus Calmette Guerin, vascular endothelial growth factor, matrix metalloproteinases, prostaglandins, reactive oxygen species, and reactive nitrogen intermediates, in addition to its synergistic effects with some anti-tuberculosis medications.
Potential Role of Vitamins A, B, C, D and E in TB Treatment and Prevention: A Narrative Review
(1) Background: Tuberculosis (TB) is one of the world’s top infectious killers, in fact every year 10 million people fall ill with TB and 1.5 million people die from TB. Vitamins have an important…
Vitamin D in Oncology
  • J. Arends
  • Medicine
    Complementary Medicine Research
  • 2011
TLDR
While supplements of vitamin D improve musculoskeletal symptoms, proof is still lacking that these doses convey a protection from cancer, Interventional studies that administer vitamin D versus placebo in patients with cancer should be a high priority.
The effects of first-line anti-tuberculosis drugs on the actions of vitamin D in human macrophages
TLDR
Vitamin D has a stimulatory effect on the mRNA expression of cathelicidin in vitro and anti-TB drugs abolish the vitamin D stimulatory effects in vitro, and subjects taking anti- TB drugs have no enhanced cathe Licidin response to vitamin D.
Vitamin D status in pediatric osteoarticular tuberculosis.
TLDR
The correlation between hypovitaminosis D and osteoarticular TB appears to be more disease specific rather than host specific.
Influence of vitamin D deficiency on T cell subsets and related indices during spinal tuberculosis
TLDR
The expression of T lymphocyte subsets in patients with vitamin D deficiency was significantly reduced, and the immune function decreased, which was not conducive to the recovery of tuberculosis lesions.
Avaliação das concentrações de vitamina D associadas a polimorfismos em genes ligados a resposta imune durante a tuberculose pulmonar ativa
TLDR
Evidence is provided of the association between VDR SNPs and Gc-globulin and serum of 25(OH)D how possible protective factors against TB and also susceptibility in Brazilian population.
Prevalence of vitamin D deficiency in adults in the coastal regions of Odisha, India
Background and objectives: Vitamin D is a fat-soluble vitamin belonging to secosteriods. It is responsible for intestinal absorption and bioavailibity of calcium and phosphorus.Synthesisof vitamin D…
Vitamin D and liver fibrosis: Molecular mechanisms and clinical studies.
TLDR
It is reasonable to postulate that vitamin D supplementation being a cost effective and relative simple procedure may benefit to liver fibrosis, but further research is needed to fully elucidate its regulatory role in inhibiting liver fibrogenesis.
Host Directed Therapies for Tuberculosis: Futures Strategies for an Ancient Disease
TLDR
This review discusses examples of potentially promising strategies aimed at improving the host response to M. tuberculosis, and argues how a better understanding of TB pathogenesis may pave the way for the design of new therapies, the identification of new drugs or the repurposing of some already in use for other diseases.
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References

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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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