• Corpus ID: 42534022

Impact of Treatment Complexity on Adherence and Glycemic Control : An Analysis of Oral Antidiabetic Agents

@inproceedings{PollackImpactOT,
  title={Impact of Treatment Complexity on Adherence and Glycemic Control : An Analysis of Oral Antidiabetic Agents},
  author={Michael F. Pollack and Benjamin Chastek and Setareh A. Williams and Janette Moran}
}
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29 Citations
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9
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Association between medication regimen complexity and pharmacotherapy adherence: a systematic review
TLDR
Although there was variability regarding the association between complexity and adherence, most studies showed that an increased regimen complexity reduces medication adherence.
Medication Regimen Complexity and Medication Burden Among Patients With Type 2 Diabetes Mellitus: A Retrospective Analysis
TLDR
High medication count, high regimen complexity, and low medication adherence were associated with poor glycemic control over the 3-month follow-up period and could be used to identify patients with complex pharmacotherapy regimens.
Adherence to and persistence with antidiabetic medications and associations with clinical and economic outcomes in people with type 2 diabetes mellitus: A systematic literature review
TLDR
Better adherence and persistence in people with T2D is associated with lower rates of microvascular and/or macrovascular outcomes and inpatient hospitalization, and lower or budget‐neutral total healthcare expenditure.
Chronic Medication Burden and Complexity for US Patients with Type 2 Diabetes Treated with Glucose-Lowering Agents
TLDR
On average, patients with type 2 diabetes used multiple medications, had a complex medication regimen, and were at potential risk of medication interactions, which suggest that patients, practitioners, pharmacists, and payers may benefit from interventions which decrease medication burden, complexity, and/or adverse events related to the treatment of T2D.
Evaluating the Impact of Outpatient Multi-Dose Medication Packaging Service (MDMPS) on Medication Adherence and Clinical Outcomes
TLDR
MDMPS can improve medication adherence, and at least 50% of patients were highly satisfied with MDMPS, and further studies are needed to understand its clinical impact.
Medication Complexity among Disadvantaged African American Seniors in Los Angeles
TLDR
Investigating correlates of MRC in African American older adults with chronic disease(s) in South Los Angeles found higher MRC correlated with female gender, a higher number of healthcare providers, hospitalization events and multimorbidity, however, there were no associations between MRC and age, level of education, financial constraint, living arrangements or health maintenance organization (HMO) membership.
Medication adherence, health care utilization, and spending among privately-insured adults with chronic conditions in the United States, 2010-2016.
Adherence to oral glucose lowering drugs, quality of life, treatment satisfaction and illness perception: A cross-sectional study in patients with type 2 diabetes
  • Rhea Farhat, J. Assaf, L. Khabbaz
  • Medicine
    Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
  • 2019
Clinical associations of an updated medication effect score for measuring diabetes treatment intensity
TLDR
The medication effect score reflects overall intensity of a diabetes regimen by consolidating dosage and potency of agents used and aims to improve understanding of medication intensity in patients with diabetes.
Medication regimen complexity and its impact on medication adherence and glycemic control among patients with type 2 diabetes mellitus in an Ethiopian general hospital
TLDR
The prevalence of high MRCImedication regimen complexity index is high among patients with T2DM and Simplification of a complex medication regimen for patients with diabetes should be sought to improve medication adherence and subsequent improvement in glycemic control.
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