Impact of RANK signalling on survival and chemotherapy response in osteosarcoma.

@article{BagHorvth2014ImpactOR,
  title={Impact of RANK signalling on survival and chemotherapy response in osteosarcoma.},
  author={Zsuzsanna Bag{\'o}-Horv{\'a}th and Katharina Schmid and Fabian R{\"o}ssler and Katalin Nagy-Bojarszky and Philipp T. Funovics and Irene Sulzbacher},
  journal={Pathology},
  year={2014},
  volume={46 5},
  pages={411-5}
}
The receptor activator of NF-κB (RANK) signalling pathway represents a promising target for the therapy of bone-related tumours. In the present study we evaluated the impact of the expression of RANK and its ligand (RANKL) on survival and response to chemotherapy in osteosarcoma patients.Expression of RANK and RANKL was examined in 91 human osteosarcomas by… CONTINUE READING