Impact of Lactoferrin and Lysozyme on Particle Diffusion and Microbial Transport in Mucus


Mucus constitutes a mesh-like hydrogel that pathogens must overcome to invade the underlying epithelium. The anti-microbial proteins, lactoferrin (LF) and lysozyme (LYS), are introduced during mucosal secretions and impact the microbiome by sequestering iron needed for bacterial growth and by lysing the cell wall. These proteins easily form ionic complexes… (More)


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