Impact of IL-28B polymorphisms on pegylated interferon plus ribavirin treatment response in children and adolescents infected with HCV genotypes 1 and 4

@inproceedings{Domagalski2012ImpactOI,
  title={Impact of IL-28B polymorphisms on pegylated interferon plus ribavirin treatment response in children and adolescents infected with HCV genotypes 1 and 4},
  author={Krzysztof Domagalski and Małgorzata Pawłowska and Andrzej Tretyn and Waldemar Halota and Malgorzata Pilarczyk and Ewa Smukalska and Katarzyna Linkowska and Tomasz Grzybowski},
  booktitle={European Journal of Clinical Microbiology & Infectious Diseases},
  year={2012}
}
IL-28B polymorphisms are predictors of response to therapy in adults infected with hepatitis C. We do not know whether they are markers of response to therapy in children and adolescents. The aim of this study was to determine whether single-nucleotide polymorphisms (SNPs) in the IL-28B gene could influence the probability of response to therapy compared with other known baseline prognostic factors and correlate with clinical findings in pediatric patients infected with hepatitis C virus (HCV… CONTINUE READING
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