Impact of Healthy Aging on Multifractal Hemodynamic Fluctuations in the Human Prefrontal Cortex

  title={Impact of Healthy Aging on Multifractal Hemodynamic Fluctuations in the Human Prefrontal Cortex},
  author={Peter Mukli and Zolt{\'a}n Nagy and Frigyes Samuel Racz and Peter Herman and Andras Eke},
  journal={Frontiers in Physiology},
Fluctuations in resting-state cerebral hemodynamics show scale-free behavior over two distinct scaling ranges. Changes in such bimodal (multi) fractal pattern give insight to altered cerebrovascular or neural function. Our main goal was to assess the distribution of local scale-free properties characterizing cerebral hemodynamics and to disentangle the influence of aging on these multifractal parameters. To this end, we obtained extended resting-state records (N = 214) of oxyhemoglobin (HbO… 

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