Impact of HIV-1 Subtype and Antiretroviral Therapy on Protease and Reverse Transcriptase Genotype: Results of a Global Collaboration

@article{Kantor2005ImpactOH,
  title={Impact of HIV-1 Subtype and Antiretroviral Therapy on Protease and Reverse Transcriptase Genotype: Results of a Global Collaboration},
  author={R. Kantor and David K. Katzenstein and Brad Efron and Ana Patricia Carvalho and Brian Wynhoven and Patricia Cane and John Clarke and Sunee Sirivichayakul and Marcelo Alves Soares and Joke Snoeck and Candice Pillay and Hagit Rudich and Ros{\^a}ngela Rodrigues and {\'A}frica Holgu{\'i}n and Koya Ariyoshi and M. Bouzas and Pedro Cahn and Wataru Sugiura and Vicente Soriano and Lu{\'i}s Fernando Br{\'i}gido and Zehava Grossman and Lynn Morris and Anne-Mieke Vandamme and Amilcar Tanuri and Praphan Phanuphak and Jonathan Weber and Deenan Pillay and P. Richard Harrigan and Ricardo Camacho and Jonathan M. Schapiro and Robert W. Shafer},
  journal={PLoS Medicine},
  year={2005},
  volume={2},
  pages={436 - 441}
}
BACKGROUND The genetic differences among HIV-1 subtypes may be critical to clinical management and drug resistance surveillance as antiretroviral treatment is expanded to regions of the world where diverse non-subtype-B viruses predominate. METHODS AND FINDINGS To assess the impact of HIV-1 subtype and antiretroviral treatment on the distribution of mutations in protease and reverse transcriptase, a binomial response model using subtype and treatment as explanatory variables was used to… CONTINUE READING

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PLoS Medicine | www.plosmedicine.org April 2005 | Volume 2 | Issue 4 | e112 0336 Subtype and Drug Impact on Genotype

S Tovanabutra, C Beyrer, S Sakkhachornphop, MH Razak, GL Ramos
AIDS Res Hum Retroviruses • 2004
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