Impact of HAART and CNS-penetrating antiretroviral regimens on HIV encephalopathy among perinatally infected children and adolescents.

@article{Patel2009ImpactOH,
  title={Impact of HAART and CNS-penetrating antiretroviral regimens on HIV encephalopathy among perinatally infected children and adolescents.},
  author={Kunjal Patel and X. T. Ming and Paige L. Williams and Kevin R. Robertson and James M. Oleske and George R. Seage},
  journal={AIDS},
  year={2009},
  volume={23 14},
  pages={
          1893-901
        }
}
OBJECTIVES Prior to antiretroviral treatment, HIV-infected children frequently developed encephalopathy, resulting in debilitating morbidity and mortality. This is the first large study to evaluate the impact of HAART and central nervous system (CNS)-penetrating antiretroviral regimens on the incidence of HIV encephalopathy and survival after diagnosis of HIV encephalopathy among perinatally infected children. DESIGN A total of 2398 perinatally HIV-infected children with at least one… CONTINUE READING

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