Impact of Global Geographic Region on Time in Therapeutic Range on Warfarin Anticoagulant Therapy: Data From the ROCKET AF Clinical Trial

@inproceedings{Singer2013ImpactOG,
  title={Impact of Global Geographic Region on Time in Therapeutic Range on Warfarin Anticoagulant Therapy: Data From the ROCKET AF Clinical Trial},
  author={Daniel E. Singer and Anne S. Hellkamp and Jonathan P Piccini and Kenneth W. Mahaffey and Yuliya V Lokhnygina and Guohua Pan and Jonathan L. Halperin and Richard C. Becker and G{\"u}nter Breithardt and Graeme J. Hankey and Werner Hacke and Christopher C. Nessel and Manesh Raman Patel and Robert M. Califf and Keith A. A. Fox},
  booktitle={Journal of the American Heart Association},
  year={2013}
}
BACKGROUND Vitamin K antagonist (VKA) therapy remains the most common method of stroke prevention in patients with atrial fibrillation. Time in therapeutic range (TTR) is a widely cited measure of the quality of VKA therapy. We sought to identify factors associated with TTR in a large, international clinical trial. METHODS AND RESULTS TTR (international normalized ratio [INR] 2.0 to 3.0) was determined using standard linear interpolation in patients randomized to warfarin in the ROCKET AF… CONTINUE READING

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