Impact of Fertility Concerns on Tamoxifen Initiation and Persistence.

@article{Llarena2015ImpactOF,
  title={Impact of Fertility Concerns on Tamoxifen Initiation and Persistence.},
  author={Natalia C. Llarena and Samantha L. Estevez and Susan L. Tucker and Jacqueline S. Jeruss},
  journal={Journal of the National Cancer Institute},
  year={2015},
  volume={107 10}
}
  • Natalia C. Llarena, Samantha L. Estevez, +1 author Jacqueline S. Jeruss
  • Published in
    Journal of the National…
    2015
  • Medicine
  • BACKGROUND Adjuvant tamoxifen reduces breast cancer recurrence risk and mortality; however, initiation and treatment persistence are poor for younger patients. We hypothesized that a unique set of factors, including fertility concerns, would contribute to the poor tamoxifen use among premenopausal patients. METHODS From 2007 to 2012, 515 premenopausal patients younger than age 45 years, with stage 0 to III hormone receptor-positive breast cancer, for whom tamoxifen was recommended, were… CONTINUE READING

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