Impact of E2F-1 expression on clinical outcome of gastric adenocarcinoma patients with adjuvant chemoradiation therapy.

@article{Lee2008ImpactOE,
  title={Impact of E2F-1 expression on clinical outcome of gastric adenocarcinoma patients with adjuvant chemoradiation therapy.},
  author={Jeeyun Lee and Cheol Keun Park and Joon Oh Park and Taekyu Lim and Young Suk Park and Ho-yeong Lim and Inkyoung Lee and Tae Sung Sohn and Jae Hyung Noh and Jin Seok Heo and Sung Hung Kim and Do Hoon Lim and Kyoung-Mee Kim and Wonyoung Kang},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2008},
  volume={14 1},
  pages={
          82-8
        }
}
PURPOSE There are no reliable prognostic markers that identify gastric cancer patients who may benefit from adjuvant chemoradiation therapy. E2F-1 was shown to be associated with radiosensitivity and chemosensitivity in certain tumor types. Therefore, we analyzed expression and prognostic significance of E2F-1 along with thymidylate synthase (TS) in R(0)-resected gastric adenocarcinoma patients, who underwent adjuvant chemoradiation therapy with 5-fluorouracil (5-FU) and leucovorin… CONTINUE READING

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 24 CITATIONS

E2F1 Expression Predicts Outcome in Korean Women Who Undergo Surgery for Breast Carcinoma

  • Annals of Surgical Oncology
  • 2009
VIEW 5 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 32 REFERENCES

American Association for Cancer clincancerres.aacrjournals.org

Clin Cancer Res Jeeyun Lee, Cheol Keun Park, Joon Oh Park
  • Research. on June
  • 2008

E 2 F - 1 overexpression in U 2 OS cells increases cyclin B 1 levels and cdc 2 kinase activity and sensitizes cells to antimitotic agents

RussoAJ, PG Magro, Z Hu
  • Cancer Res
  • 2006

Adenoviral - E 2 F - 1 radiosensitizes p 53 wild - type and p 53 null human prostate cancer cells

KH Nguyen, P Hachem, LY Khor
  • Int J Radiat Oncol Biol Phys
  • 2005