Impact of DNA damage on the frequency of sperm chromosomal aneuploidy in normal and subfertile men.

@article{Nili2011ImpactOD,
  title={Impact of DNA damage on the frequency of sperm chromosomal aneuploidy in normal and subfertile men.},
  author={Hamid Alizadeh Nili and Hossein Mozdarani and Franck Pellestor},
  journal={Iranian biomedical journal},
  year={2011},
  volume={15 4},
  pages={122-9}
}
BACKGROUND Various frequencies of sperm aneuploidy are reported in sperms of subfertile patients compared to normal individuals. Moreover, sperm DNA damage is shown to be associated with male infertility. In this study, the rate of DNA damage and frequencies of aneuploidy in sperms of subfertile patients was investigated. METHODS Semen samples were obtained from healthy normal and subfertile (oligozoospermia, asthenozoospermia, and oligoasthenozoospermia) men. The frequency of aneuploidy was… CONTINUE READING