Impact-Free Measurement of Microtubule Rotations on Kinesin and Cytoplasmic-Dynein Coated Surfaces

@inproceedings{Mitra2015ImpactFreeMO,
  title={Impact-Free Measurement of Microtubule Rotations on Kinesin and Cytoplasmic-Dynein Coated Surfaces},
  author={Aniruddha Mitra and Felix Ruhnow and Bert Nitzsche and Stefan Diez and Monica Soncini},
  booktitle={PloS one},
  year={2015}
}
Knowledge about the three-dimensional stepping of motor proteins on the surface of microtubules (MTs) as well as the torsional components in their power strokes can be inferred from longitudinal MT rotations in gliding motility assays. In previous studies, optical detection of these rotations relied on the tracking of rather large optical probes present on… CONTINUE READING