Immunotoxin therapy of cancer.

  title={Immunotoxin therapy of cancer.},
  author={Arthur Edward Frankel},
  volume={7 5},
  pages={69-78; discussion 79-80, 83-6}
Differentiation antigens, hormones and growth factor receptors, and viral antigens are expressed on the surface of a variety of malignant and dysfunctional cells in humans. Murine and human monoclonal antibodies, recombinant hormone and growth factors, and recombinant soluble viral glycoprotein receptors have been generated that can target diseased human cells in vitro and in vivo. Highly potent peptide toxins that catalytically inactivate protein synthesis have been linked both chemically and… CONTINUE READING

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