Immunotoxicity of nanoparticles: a computational study suggests that CNTs and C60 fullerenes might be recognized as pathogens by Toll-like receptors.

@article{Turabekova2014ImmunotoxicityON,
  title={Immunotoxicity of nanoparticles: a computational study suggests that CNTs and C60 fullerenes might be recognized as pathogens by Toll-like receptors.},
  author={Malakhat A. Turabekova and Bakhtiyor F. Rasulev and Melanie Theodore and Joany Jackman and Daria Leszczyńska and Jerzy Leszczynski},
  journal={Nanoscale},
  year={2014},
  volume={6 7},
  pages={3488-95}
}
Over the last decade, a great deal of attention has been devoted to study the inflammatory response upon exposure to multi/single-walled carbon nanotubes (CNTs) and different fullerene derivatives. In particular, carbon nanoparticles are reported to provoke substantial inflammation in alveolar and bronchial epithelial cells, epidermal keratinocytes, cultured monocyte-macrophage cells, etc. We suggest a hypothetical model providing the potential mechanistic explanation for immune and… CONTINUE READING
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