Immunotherapy with cat- and dog-dander extracts. II. In vivo and in vitro immunologic effects observed in a 1-year double-blind placebo study.

@article{Hedlin1986ImmunotherapyWC,
  title={Immunotherapy with cat- and dog-dander extracts. II. In vivo and in vitro immunologic effects observed in a 1-year double-blind placebo study.},
  author={Gunilla Hedlin and V Graff-Lonnevig and H Heilborn and G. Patrick Lilja and K Norrlind and K O Pegelow and Birgitta Sundin and Henning L\owenstein},
  journal={The Journal of allergy and clinical immunology},
  year={1986},
  volume={77 3},
  pages={488-96}
}
The effects of immunotherapy on the skin prick test, allergen-specific IgE, and IgG in 39 patients (19 adults and 20 children), treated with partially purified cat- or dog-dander extracts or placebo for 1 year, were studied by use of a double-blind protocol. IgG levels were measured by three different assays: IgG RAST, IgG4 RAST, and Staph A IgG1, 2, and 4. The skin prick test reaction decreased continuously in the allergen-treated patients, the decrease being the first sign of an immunologic… CONTINUE READING

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