Immunotherapy of type 1 diabetes: lessons for other autoimmune diseases

  • J F Bach
  • Published 2002 in Arthritis research

Abstract

The nonobese diabetic (NOD) mouse is a well-recognised animal model of spontaneous autoimmune insulin-dependent diabetes mellitus. The disease is T-cell mediated, involving both CD4 and CD8 cells. Its progress is controlled by a variety of regulatory T cells. An unprecedented number of immunological treatments have been assessed in this mouse strain. This… (More)
DOI: 10.1016/j.jaut.2008.04.026

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Cite this paper

@inproceedings{Bach2002ImmunotherapyOT, title={Immunotherapy of type 1 diabetes: lessons for other autoimmune diseases}, author={J F Bach}, booktitle={Arthritis research}, year={2002} }