Immunotherapy of tumors with autologous tumor-derived heat shock protein preparations.

@article{Tamura1997ImmunotherapyOT,
  title={Immunotherapy of tumors with autologous tumor-derived heat shock protein preparations.},
  author={Yoshihisa Tamura and Pel Peng and K Liu and M C Daou and Pramod K Srivastava},
  journal={Science},
  year={1997},
  volume={278 5335},
  pages={
          117-20
        }
}
Immunotherapy of mice with preexisting cancers with heat shock protein preparations derived from autologous cancer resulted in retarded progression of the primary cancer, a reduced metastatic load, and prolongation of life-span. Treatment with heat shock protein preparations derived from cancers other than the autologous cancer did not provide significant protection. Spontaneous cancers (lung cancer and melanoma), chemically induced cancers (fibrosarcoma and colon carcinoma), and an ultraviolet… CONTINUE READING

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