Immunotherapy of melanoma with the immune costimulatory monoclonal antibodies targeting CD137

@article{Li2013ImmunotherapyOM,
  title={Immunotherapy of melanoma with the immune costimulatory monoclonal antibodies targeting CD137},
  author={Shiyan Li and Yizhen Liu},
  journal={Clinical Pharmacology : Advances and Applications},
  year={2013},
  volume={5},
  pages={47 - 53}
}
  • Shiyan Li, Yizhen Liu
  • Published 2013
  • Medicine
  • Clinical Pharmacology : Advances and Applications
  • Knowledge of how the immune system recognizes and attempts to control cancer growth and development has improved dramatically. The advent of immunotherapies for cancer has resulted in robust clinical responses and confirmed that the immune system can significantly inhibit tumor progression. Until recently, metastatic melanoma was a disease with limited treatment options and a poor prognosis. CD137 (also known as 4-1BB) a member of the tumor necrosis factor (TNF) receptor superfamily, is an… CONTINUE READING
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