Immunotherapy of acute myeloid leukaemia: development of a whole cell vaccine.

@article{Cheuk2008ImmunotherapyOA,
  title={Immunotherapy of acute myeloid leukaemia: development of a whole cell vaccine.},
  author={Adam T. C. Cheuk and Barbara-ann Guinn},
  journal={Frontiers in bioscience : a journal and virtual library},
  year={2008},
  volume={13},
  pages={2022-9}
}
Acute myeloid leukaemia (AML) is a difficult to treat disease and strategies, such as immunotherapy, which have the potential to eliminate residual tumour cells at first remission are required to reduce the incidence of relapse with its high associated mortality rates. T cells play an important role in tumor immunity and two signals are traditionally thought to be required to activate naive T cells; signal one through the major histocompatibility:antigen:T-cell receptor complex and signal two… CONTINUE READING