Immunotherapy for the treatment of prostate cancer

  title={Immunotherapy for the treatment of prostate cancer},
  author={G. Lorenzo and C. Buonerba and P. W. Kantoff},
  journal={Nature Reviews Clinical Oncology},
  • G. Lorenzo, C. Buonerba, P. W. Kantoff
  • Published 2011
  • Medicine
  • Nature Reviews Clinical Oncology
  • Failure of immune surveillance has a prominent role in tumorigenesis. Cancerous cells can evade T-cell responses to tumor-associated antigens by multiple mechanisms. Active immunotherapy aims to stimulate the immune response against cancer cells. Unlike normal prostate tissue, prostate cancer is not ignored by the immune system, as shown by the presence of tumor infiltrating lymphocytes. This characteristic renders prostate cancer particularly suitable for immunotherapy. The existence of well… CONTINUE READING
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